Night Vale General Hospital appears to be the main health care provider--and the only trauma care provider--of the city of Night Vale. It has a cancer ward, a labor and delivery ward, and a helicopter pad .
- Episode 6 The Drawbridge: Juanita Jefferson is airlifted to the hospital.
- Episode 9 "PYRAMID": Surgeons affiliated with the hospital note an uptick in unusual skin growths, such as 15-inch spiral horns, and caution townspeople to wear sunscreen.
- Episode 18 The Traveler: Megan Wallaby is born at the hospital, as is Cactus Jane's son Champ.
- Episode 24 The Mayor: Mayor Pamela Winchell announces increased funding for the cancer ward.
- Episode 40 The Deft Bowman: